High in ESTER C promote youthful-looking skin & help erase sun spot and discoloration. Research shows that ESTER C lightens, protects and plums skin cells.
Radiant Skin Therapeutic Serum
Lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial.
Antioxidants are becoming increasingly important in the treatment of skin disease. In addition to their known anti-inflammatory effects, antioxidants may act to prevent the oxidation of sebum which has been proposed to be comedogenic in acne patients. Sodium L-ascorbyl-2-phosphate (APS) is a stable vitamin C derivative and highly effective antioxidant that has demonstrated efficacy in acne in open label studies. Objective To evaluate the efficacy and safety of APS 5% lotion for the treatment of acne in a blinded controlled study. Methods A total of 50 subjects were randomized in a double-blind controlled trial to receive APS 5% lotion or vehicle for 12 weeks. Evaluation included an Investigator’s Global Assessment Score, a Subjects’ Global Assessment Score, lesion counts, cutaneous tolerability, and adverse events. Results APS 5% lotion demonstrated statistically significant improvement when compared to v
ehicle in all of the parameters measured. The adverse event frequency and cutaneous tolerability profile for APS 5% lotion were similar to vehicle. Limitations Adjunctive topical or oral agents and their impact on acne were not studied in this trial. Conclusions This study demonstrates that 5% sodium L-ascorbyl-2-phosphate is efficacious as monotherapy for the treatment of acne. APS 5% lotion offers a novel addition to our current acne armamentarium.
Woolery-Lloyd, H., Baumann, L., & Ikeno, H. (2010). Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trial. Journal Of Cosmetic Dermatology, 9(1), 22-27. doi:10.1111/j.1473-2165.2010.00480.
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